Monthly Archives: December 2016

Our review on the 4D nucleome in single cells

Sekelja M, Paulsen J, Collas P. 2016. 4D nucleomes in single cells: what can computational modeling reveal about spatial chromatin conformation?¬†Genome Biol. 2016, 17:54. PMID:27052789 Abstract: Genome-wide sequencing technologies enable investigations of the structural properties of the genome in various spatial dimensions. Here, we review computational techniques developed to model the three-dimensional genome in single…
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