Lamins and lamina-associated domains in the establishment of cell identity

Project participants

Julia Madsen-Østerbye, Anita Sørensen, Kristin Vekterud, Mohamed Abdelhalim 

Ongoing research

  • Regulation of nuclear lamina interactions with chromatin via LADs and sub-LAD microdomains during adipose differentiation
  • Role of A- and B-type lamins on lineage-specific differentiation of adipose stem cells

Our work relies on mechanistic cell biology and genomic approaches using engineered cell lines and primary mesenchymal stem cells.

Recent findings