Our recent publications
2026
Hazell Pickering S, Galigniana NM, Abdelhalim M, Sørensen AL, Madsen-Østerbye J, Zucknick M, Collas P, Briand N. 2026. Multimodal epigenetic and enhancer network remodeling shape the transcriptional landscape of human beige adipocytes. Commun Biol. Jan 8. doi: 10.1038/s42003-025-09469-8
Genome Res 36(1):20-37.
2025
Vatier C, Araújo-Vilar D, et al. 2025. Proceedings of the annual meeting of the European Consortium of Lipodystrophies (ECLip) Paris, France, 20-21 May 2025. Ann Endocrinol; 86(5):102432.
2024
Nutrients 16(24):4310
Front Endocrinol. 15:1395750.
Commun Biol. 15;7(1):458.
2023
Voon HPJ, Hii L, Garvie A, Udugama M, Krug B, Russo C, Chüeh AC, Daly RJ, Morey A, Bell TDM, Turner SJ, Rosenbluh J, Daniel P, Firestein R, Mann JR, Collas P, Jabado N, Wong LH. 2023. Pediatric glioma histone H3.3 K27M/G34R mutations drive abnormalities in PML nuclear bodies. Genome Biol. 24(1):284
Russ BE, Barugahare A, Dakle P, Tsyganov K, Quon S, Yu B, Li J, Lee JKC, Olshansky M, He Z, Harrison PF, See M, Nussing S, Morey AE, Udupa VA, Bennett TJ, Kallies A, Murre C, Collas P, Powell D, Goldrath AW, Turner SJ. 2023. Active maintenance of CD8+ T cell naivety through regulation of global genome architecture. Cell Rep. 42(10):113301
Nucleic Acids Res 51(20):11024-11039.
Genes 14, 334
2023. Cellular and Genomic Features of Muscle Differentiation from Isogenic Fibroblasts and Myoblasts. Cells 12(15):1995
2022
Potolitsyna E, Hazell Pickering S, Tooming-Klunderud A, Collas P, Briand N. 2022. De novo annotation of lncRNA HOTAIR transcripts by long-read RNA capture-seq reveals a differentiation-driven isoform switch BMC Genomics 23, 658
Kuo FC, Neville MJ, Sabaratnam R, Wesolowska-Andersen A, Phillips D, Wittemans LBL, van Dam AD, Loh NY, Todorčević M, Denton N, Kentistou KA, Joshi PK, Christodoulides C, Langenberg C, Collas P, Karpe F, Pinnick KE. 2022. HOTAIR interacts with PRC2 complex regulating the regional preadipocyte transcriptome and human fat distribution Cell Rep 40, 111136
Potolitsyna E, Hazell Pickering S, Germier T, Collas P, Briand N. 2022. Long non-coding RNA HOTAIR regulates cytoskeleton remodeling and lipid storage capacity during adipogenesis Sci Rep 12, 10157
Madsen-Østerbye J, Bellanger A, Galigniana NM, Collas P. 2022. Biology and Model Predictions of the Dynamics and Heterogeneity of Chromatin-Nuclear Lamina Interactions Front Cell Dev Biol 10, 913458
Bellanger A, Madsen-Østerbye J, Galigniana NM, Collas P. 2022. Restructuring of Lamina-Associated Domains in Senescence and Cancer Cells 11, 1846
Madsen-Østerbye J, Abdelhalim M, Baudement MO, Collas P. 2022. Local euchromatin enrichment in lamina-associated domains anticipates their repositioning in the adipogenic lineage . Genome Biol 23, 91
Udugama M, Vinod B, Chan FL, Hii L, Garvie A, Collas P, Kalitsis P, Steer D, Das PP, Tripathi P, Mann JR, Voon HPJ, Wong LH. 2022. Histone H3.3 phosphorylation promotes heterochromatin formation by inhibiting H3K9/K36 histone demethylase. Nucleic Acids Res 50, 4500-4514
Methods Mol Biol 301, 337-352
2021
BMC Genomics 22, 499
Mutations inhibiting KDM4B drive ALT activation in ATRX-mutated glioblastomas. Nat Commun 12, 2584
Physical constraints in polymer modeling of chromatin associations with the nuclear periphery at kilobase scale. Nucleus 12, 6-20
2020
Vietri M, Schultz SW, Bellanger A, Jones CM, Petersen LI, Raiborg C, Skarpen E, Pedurupillay CRJ, Kjos I, Kip E, Timmer R, Jain A, Collas P, Knorr RL, Grellscheid SN, Kusumaatmaja H, Brech A, Micci F, Stenmark H, Campsteijn C. 2020. Unrestrained ESCRT-III drives micronuclear catastrophe and chromosome fragmentation. Nat Cell Biol 22, 856-867
Briand N, Collas P. 2020. Lamina-associated domains: peripheral matters and internal affairs. Genome Biol 21, 85
Brunet A, Forsberg F, Fan Q, Sæther T, Collas P. 2019. Nuclear Lamin B1 Interactions With Chromatin During the Circadian Cycle Are Uncoupled From Periodic Gene Expression. Front Genet 10, 917
Ménard C, Dulong J, Roulois D, Hébraud B, Verdière L, Pangault C, Sibut V, Bezier I, Bescher N, Monvoisin C, Gadelorge M, Bertheuil N, Flécher E, Casteilla L, Collas P, Sensebé L, Bourin P, Espagnolle N, Tarte K. 2020. Integrated transcriptomic, phenotypic, and functional study reveals tissue-specific immune properties of mesenchymal stromal cells. Stem Cells 38, 146-159
2019
Paulsen J, Liyakat Ali TM, Nekrasov M, Delbarre E, Baudement MO, Kurscheid S, Tremethick D, Collas P. 2019. Long-range interactions between topologically associating domains shape the four-dimensional genome during differentiation. Nature Genet 51, 835-843
Forsberg F, Brunet A, Liyakat Ali TM, Collas P. 2019. Interplay of lamin A and lamin B LADs on the radial positioning of chromatin. Nucleus 10, 7-20
Spirkoski J, Shah A., Reiner AH, Collas P., Delbarre E. 2019. ML modulates H3.3 targeting to telomeric and centromeric repeats in mouse fibroblasts. Biochem Biophys Res Com 511, 882-888
2018
Briand N., Cahyani I., Madsen-Østerbye J., Paulsen J., Rønningen T., Sørensen A.L., Collas P. 2018. Lamin A, chromatin and FPLD2: not just a peripheral ménage-à-trois. Front Cell Dev Biol doi: 10.3389/fcell.2018.00073
Paulsen J, Liyakat Ali TM, Collas P. 2018. Computational 3D genome modeling using Chrom3D. Nature Protoc 13, 1137-1152.
Udugama M, Sanij E, Voon HPJ, Son J, Hii L, Henson JD, Chan FL, Chang FTM, Liu Y, Pearson RB, Kalitsis P, Mann JR, Collas P, Hannan RD, Wong LH. 2018. Ribosomal DNA copy loss and repeat instability in ATRX-mutated cancers. Proc Natl Acad Sci USA 115, 4737-4742.
Rogne M, Chu DT, Küntziger TM, Mylonakou MN, Collas P, Tasken K. 2018. OPA1-anchored PKA phosphorylates perilipin 1 on S522 and S497 in adipocytes differentiated from human adipose stem cells. Mol Biol Cell 29, 1487-1501.
Briand N, Guénantin AC, Jeziorowska D, Shah A, Mantecon M, Capel E, Garcia M, Oldenburg A, Paulsen J, Hulot JS, Vigouroux C, Collas P. 2018. The lipodystrophic hotspot lamin A p.R482W mutation deregulates the mesodermal inducer T/Brachyury and early vascular differentiation gene networks. Hum Mol Genet 27, 1447-1459.
2017
Paulsen J, Sekelja M, Oldenburg AR, Barateau A, Briand N, Delbarre E, Shah, A, Sørensen AL, Vigouroux C, Biendia B, Collas P. 2017. Chrom3D: three-dimensional genome modeling from Hi-C and nuclear lamin-genome contacts. Genome Biol 18, 21.
Guénantin AC, Briand N, Capel E, Dumont F, Morichon R, Provost C, Stillitano F, Jeziorowska D, Siffroi JP, Hajjar RJ, Fève B, Hulot JS, Collas P, Capeau J, Vigouroux C. 2017. Functional Human Beige Adipocytes from Induced Pluripotent Stem Cells. Diabetes 66, 1470-1478.
Delbarre E, Ivanauskiene K, Spirkoski J, Shah A, Vekterud K, Moskaug JØ, Bøe SO, Wong LH, Küntziger T, Collas P. 2017. PML protein organizes heterochromatin domains where it regulates histone H3.3 deposition by ATRX/DAXX. Genome Res 27, 913-921.
Oldenburg AR, Briand N, Sørensen AL, Cahyani I, Shah A, Moskaug JØ, Collas P. 2017. A lipodystrophy-causing lamin A mutant alters conformation and epigenetic regulation of the anti-adipogenic MIR335 locus. J Cell Biol 216, 2731-2743.
Garcia-Nieto PE, Schwartz E, King DA, Paulsen J, Collas P, Herrera RE, Morrison AJ. 2017. Carcinogen susceptibility is regulated by genome architecture and dictates cancer mutagenenesis. EMBO J. 36, 2839-2843.