Invited lecture (Philippe): Gene regulatory interactions at lamina-associated domains
Read more
We speak at the Gordon Research Conference on Genome architecture in cell fate and disease 2023, in Ventura, CA, USA
Invited lecture (Philippe): The dynamic 3D genome: a tale of LADs
Read more
New presentation at the 4th International Meeting on Laminopathies, Madrid, Spain
Invited lecture (Philippe): Chromatin (de)regulation in laminopathies
Read more
Our latest paper, on enhancer loops at the nuclear lamina, is out!
The nuclear lamina provides a repressive chromatin environment at the nuclear periphery. However, whereas most genes in lamina-associated domains (LADs) are inactive, over ten percent reside in local euchromatic contexts and are expressed. How these genes are regulated and whether they are able to interact with regulatory elements remain unclear. Here, we integrate publicly available…
Read more