Chromatin architecture in lipodystrophic laminopathies

Project participants

Nolwenn Briand, Louise Petersen, Julia Madsen-Østerbye, Anita Sørensen; collaborations with Coen Campsteijn (U Oslo), Corinne Vigouroux and Isabelle Jéru (INSERM & Université Pierre et Marie Curie, Paris)

Ongoing research

  • Impact of FPLD2-causing lamin A p.R482W mutation on functional nuclear and chromatin architecture during adipogenesis and in adipocytes
  • Impact of lamin A p.R482W on nuclear envelope integrity


Recent achievements