Welcome to CollasLab
Nuclear architecture of adipogenesis
We investigate mechanisms by which 3D nuclear architecture patterns lineage determination of adipose progenitor cells into lipid-storing white adipocytes and thermogenic beige adipocytes, in health and disease states (lipodystrophic laminopathies & metabolic syndrome).
Read more >>Meet our team >>
Philippe Collas, Professor, Principal Investigator
Chair, Department of Molecular Medicine
Mailing address:
University of Oslo
Institute of Basic Medical Sciences
Department of Molecular Medicine
PO Box 1112 Blindern
0317 Oslo, Norway
Visiting address:
University of Oslo
Domus Medica, 2nd floor, room 2250
Sognvannsveien 9
0372 Oslo, Norway
Public transport: Tram lines 17 and 18 to Rikshospitalet; get off at the end station and walk to Domus Medica.
Phone: +47 22851060 (Administrative assistant)
philc [at] medisin.uio.no
s.m.taraldsen [at] medisin.uio.no (Administrative assistant)
s.m.taraldsen [at] medisin.uio.no (Administrative assistant)
We are working in the following areas:
Our work combines molecular, genomics, imaging and computational modeling approaches using patient material and engineered progenitor cells from human adipose tissue.
Go to research >>Funding
- University of Oslo
- The Research Council of Norway
- The Norwegian Cancer Society
- South-East Health Norway
News
An updated description of our pipeline for modeling the 3D genome using Hi-C and LAD data (Chrom3D) is out!
3D genome organization is shaped by dynamic interactions with multiple structures in the nucleus, affecting gene expression outcomes. Technological breakthroughs have generated vast datasets reflecting various aspects of nuclear genome…Check out our latest paper on how TAD cliques predict key features of chromatin organization
Our paper characterizing the genomic composition of so-called TAD cliques (Paulsen et al. 2019 Nat Genet) is out in BMC Genomics (Liyakat Ali et al. 2021 BMC Genomics 22, 499;…New 5-year funding from the Transdiscipline Program of the Research Council of Norway to investigate the impact of adolescence sleep deprivation on adult metabolic health (SmartSense)
Obesity and bad sleep habits among teenagers are two rising health concerns that are intertwined. We have secured a 5-year funding to study how sleep deprivation during adolescence affects fat…
An updated description of our pipeline for modeling the 3D genome using Hi-C and LAD data (Chrom3D) is out!
3D genome organization is shaped by dynamic interactions with multiple structures in the nucleus, affecting gene expression outcomes. Technological breakthroughs have generated vast datasets reflecting various aspects of nuclear genome…
Check out our latest paper on how TAD cliques predict key features of chromatin organization
Our paper characterizing the genomic composition of so-called TAD cliques (Paulsen et al. 2019 Nat Genet) is out in BMC Genomics (Liyakat Ali et al. 2021 BMC Genomics 22, 499;…
New 5-year funding from the Transdiscipline Program of the Research Council of Norway to investigate the impact of adolescence sleep deprivation on adult metabolic health (SmartSense)
Obesity and bad sleep habits among teenagers are two rising health concerns that are intertwined. We have secured a 5-year funding to study how sleep deprivation during adolescence affects fat…