Welcome to CollasLab

Nuclear architecture of adipogenesis

bureauxWe investigate mechanisms by which 3D nuclear architecture patterns differentiation of adipose progenitor cells into specific adipocyte sub-types, such as lipid-storing white adipocytes and thermogenic beige adipocytes.  We examine how mutations in nuclear lamins causing familial partial lipodystrophy (FPLD2, a subset of laminopathies) affect chromatin architecture and adipogenic differentiation in upper and lower body fat depots. We also study aspects of nuclear envelope dynamics.
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Meet our team >>

Philippe Collas, Professor, Head of Laboratory

Mailing address:
University of Oslo
Institute of Basic Medical Sciences
Department of Molecular Medicine
PO Box 1112 Blindern
0317 Oslo, Norway

Visiting address:
University of Oslo
Domus Medica, 2nd floor, room 2250
Sognvannsveien 9
0372 Oslo, Norway

Public transport: Tram lines 17 and 18 to Rikshospitalet; get off at the end station and walk to Domus Medica.

Phone: +47 22851060 (Administrative assistant)

philc [at] medisin.uio.no
s.m.taraldsen [at] medisin.uio.no (Administrative assistant)

We are working in the following areas:

Our work combines molecular, genomics, imaging and computational modeling approaches using patient material and engineered progenitor cells isolated from human adipose tissue.

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Funding

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