Welcome to CollasLab
Nuclear and chromatin architecture in adipose stem cells and cancer cells
The CollasLab investigates principles of 3D genome architecture which pattern lineage-specific stem cell differentiation in health and disease.
Our lab consists of 16 scientists, postdocs, PhD students and technicians working to understand mechanisms regulating chromatin plasticity in adipose tissue, pediatric glioblastomas, and breast cancer.
Meet our team >>[/lazy_load_box]
Philippe Collas, Professor
Mailing adress:
University of Oslo
Institute of Basic Medical Sciences
Department of Molecular Medicine
PO Box 1112 Blindern
0317 Oslo, Norway
Delivery and visiting address:
University of Oslo
Domus Medica, 2nd floor, room 2247
Sognvannsveien 9
0372 Oslo, Norway
(Public transport: Tram lines 17 and 18 to Rikshospitalet; get off at end station; go to Domus Medica)
Phone: +47 22851060 (Administrative assistant)
s.m.taraldsen [at] medisin.uio.no (Administrative assistant)
We are working in the following areas:
Our work combines molecular, genomics, imaging and computational modeling approaches using patient material and engineered stem and cancer cells.
Go to research >>[/lazy_load_box]CollasLab funding:
- University of Oslo
- The Research Council of Norway
- The Norwegian Cancer Society
- South-East Health Norway
News
Our paper on TAD cliques is out in Nature Genetics
Nat Genet. 2019 May;51(5):835-843. doi: 10.1038/s41588-019-0392-0. Long-range interactions between topologically associating domains shape the 4-dimensional genome during differentiation Jonas Paulsen, Tharvesh M. Liyakat Ali, Maxim Nekrasov, Erwan Delbarre, Marie-Odile Baudement,…Lipodystrophic Lamin A mutation deregulates MIR335 in pre-adipocytes
J Cell Biol. 2017 Sep 4;216(9):2731-2743. doi: 10.1083/jcb.201701043. Epub 2017 Jul 27. A lipodystrophy-causing lamin A mutant alters conformation and epigenetic regulation of the anti-adipogenic MIR335 locus. Oldenburg A1,…
[/lazy_load_box]Our paper on TAD cliques is out in Nature Genetics
Lipodystrophic Lamin A mutation deregulates MIR335 in pre-adipocytes
Meet our collaborators
