Nat Genet. 2019 May;51(5):835-843. doi: 10.1038/s41588-019-0392-0. Long-range interactions between topologically associating domains shape the 4-dimensional genome during differentiation Jonas Paulsen, Tharvesh M. Liyakat Ali, Maxim Nekrasov, Erwan Delbarre, Marie-Odile Baudement, Sebastian Kurscheid, David Tremethick and Philippe Collas A collaboration between the University of Oslo (Collas) and The Australian National University (Tremethick) Genomic information is selectively…
Read more
About: Philippe Collas
Recent Posts by Philippe Collas
Lipodystrophic Lamin A mutation deregulates MIR335 in pre-adipocytes
J Cell Biol. 2017 Sep 4;216(9):2731-2743. doi: 10.1083/jcb.201701043. Epub 2017 Jul 27. A lipodystrophy-causing lamin A mutant alters conformation and epigenetic regulation of the anti-adipogenic MIR335 locus. Oldenburg A1, Briand N1, Sørensen AL1, Cahyani I1, Shah A1, Moskaug JØ1,2, Collas P3,2. Abstract Mutations in the Lamin A/C (LMNA) gene-encoding nuclear LMNA cause laminopathies, which…
Read more
Lipodystrophic Lamin A mutation deregulates mesodermal differentiation in iPS cell model of FPLD2
Hum Mol Genet. 2018 Apr 15;27(8):1447-1459. doi: 10.1093/hmg/ddy055. The lipodystrophic hotspot lamin A p.R482W mutation deregulates the mesodermal inducer T/Brachyury and early vascular differentiation gene networks. Briand N1,2, Guénantin AC2,3, Jeziorowska D4, Shah A1, Mantecon M2, Capel E2, Garcia M2, Oldenburg A1, Paulsen J1, Hulot JS4, Vigouroux C2,5, Collas P1,6. Abstract The p.R482W hotspot mutation…
Read more
Chrom3D protocol published in Nature Protocols
Computational 3D genome modeling using Chrom3D Nat Protoc. 2018 May;13(5):1137-1152. doi: 10.1038/nprot.2018.009. Epub 2018 Apr 26. Paulsen J1, Liyakat Ali TM1, Collas P1,2. 1 Department of Molecular Medicine, Institute of Basic Medical Sciences, Faculty of Medicine, University of Oslo, Oslo, Norway. 2 Department of Immunology, Oslo University Hospital, Oslo, Norway. Chrom3D is a computational platform…
Read more
- 1
- 2
Recent Comments by Philippe Collas
No comments by Philippe Collas yet.