Computational 3D genome modeling using Chrom3D Nat Protoc. 2018 May;13(5):1137-1152. doi: 10.1038/nprot.2018.009. Epub 2018 Apr 26. Paulsen J1, Liyakat Ali TM1, Collas P1,2. 1 Department of Molecular Medicine, Institute of Basic Medical Sciences, Faculty of Medicine, University of Oslo, Oslo, Norway. 2 Department of Immunology, Oslo University Hospital, Oslo, Norway. Chrom3D is a computational platform…
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Genome structures in Virtual Reality
Our Chrom3D genome structures visualized in Virtual Reality by master student Magnus Elden. https://youtu.be/eD8atMKqknA
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Chrom3D: a scalable whole-genome 3D modeling framework
Chrom3D: three-dimensional genome modeling from Hi-C and nuclear lamin-genome contacts. Genome Biology. 2017. 18:21. Abstract Current 3-dimensional (3D) genome modeling platforms are limited by their inability to account for radial placement of loci in the nucleus. We present Chrom3D, a user-friendly whole-genome 3D computational modeling framework that simulates positions of topologically-associated domains (TADs) relative to…
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