We study how A-type lamins and microproteins regulate the activity of pioneer transcription factors implicated in EMT and cancer metastasis.
Nuclear lamina / transcription factor / microprotein interplay in cancer
3D epigenetic control of white / beige adipocyte identity
We examine 3D epigenetic mechanisms regulating adipose progenitor fate specification , and in white vs. thermogenic beige adipogenesis.
Genome organization in laminopathies
We study how laminopathy-causing lamin A mutations affect genome organization and transcription control in adipose progenitors and adipocytes, and in